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>> Presentationsはこちら

 

2018


  1. T. Oikawa, Y. Ishimaru, S. Munemasa, Y. Takeuchi, K. Washiyama, S. Hamamoto, N. Yoshikawa, Y. Murata, N. Uozumi, M. Ueda, Ion channels regulate nyctinastic leaf opening in Samanea saman, Current Biology, accepted (2018).


  1. Y. Ishimaru, K. Hayashi, T. Suzuki, H. Fukaki, J. Prusinska, C. Meester, M. Quareshy, S. Egoshi, H. Matsuura, K. Takahashi, N. Kato, E. Kombrink, R. M. Napier, K. Hayashi, M. Ueda, Jasmonic acid preferentially inhibits auxin-induced lateral root in a COI1-independent manner, Plant Physiol., accepted (2018)


  1. M. Ueda, K. Hayashi, S. Egoshi, Y. Ishimaru, Y. Takaoka, K. Dodo, and M. Sodeoka, The alkyne-tag Raman imaging of coronatine, a plant pathogen virulence factor, in Commelina communis and the possible mode of action, Org. Biomol. Chem., 16, 3348-3352 (2018) | DOI: 10.1039/C8OB00097B, Selected as a front cover picture.


  1. S. Tamura‡, M. Okada‡, S. Kato, Y. Shinoda, N. Shioda, K. Fukunaga, K. Tei-Ui, M. Ueda, (‡co-first authors), Ouabagenin is a naturally occurring LXR ligand without causing hepatic steatosis, Sci. Rep., 8:2305 (2018) | DOI:10.1038/s41598-018-20663-z.


  1. S. Saito, S. Hamamoto, K. Moriya, A. Matsuura, Y. Sato, J. Muto, H. Noguchi, S. Yamauchi, Y. Tozawa, M. Ueda, K. Hashimoto, P. Köster, Q. Dong, K. Held, J. Kudla, T. Utsumi, and N. Uozumi, Dual Lipid Modification is Prevalent in Specific Kinase Families and Required for SLAC1 Activation, New Phytologist., 218, 1504-1521 (2018) | DOI: 10.1111/nph.15053


  1. Y. Takaoka, M. Ueda, Enantiodifferential approach for the target protein detection of the jasmonate glucoside that controls the leaf closure of Samanea saman in `Plant Chemical Genomics`, Friedrich Fauser and Martin Jonikas (Eds), (‘Methods in Molecular Biology’ Vol.1795), Springer Nature, in press (2018).


  1. 田村 理、岡田麻衣子、上田 実、「強心性配糖体アグリコン ウアバインの新規生理活性」、化学と生物(遠藤 章先生ガードナー賞受賞記念特集号)、56、p.184-189 (2018).



2017


  1. M. Ueda, S. Egoshi, K. Dodo, Y. Ishimaru, H. Yamakoshi, T. Nakano, Y. Takaoka, S. Tsukiji, M. Sodeoka, Non-canonical function of a small-molecular virulence factor coronatine against plant immunity: An In vivo Raman imaging approach, ACS Central Science, 3, 462-472 (2017). DOI: 10.1021/acscentsci.7b00099


  1. Y. Takaoka, Y. Nukadzuka, M. Ueda, Reactive group-embedded affinity labeling reagent for efficient intracellular protein labeling, Bioorg. Med. Chem. (invited paper), 25, 2888-2894 (2017).


  1. Y. Takaoka, M. Imai, M. Shigenaga, M. Ueda, Design and synthesis of a second-generation ligand-tethered calcium indicator for plant cell biology based on the fundamental analyses of the structure and physical property, Tetrahedron, 73, 3079-3085 (2017).


  1. Y. Ishimaru, T. Oikawa, T. Suzuki, H. Matsuura, K. Takahashi, S. Takeishi, S. Hamamoto, N. Uozumi, T. Shimizu, M. Seo, H. Ohta, M. Ueda, GTR1 is a jasmonic acid and jasmonoyl-L-isoleucine transporter in Arabidopsis thaliana, Biosci. Biotechnol. Biochem., 81, 249-255 (2017). Selected as a cover picture.


  1. Y. Ishimaru, K. Washiyama, T. Oikawa, S. Hamamoto, N. Uozumi, and M. Ueda, Dimerization of GTR1 regulates their plasmamembrane localization, Plant Signal. Behav., 12, - (2017).


  1. H. Oishi, Y. Takaoka, T. Nishimaki-Mogami, H. Saito, M. Ueda, A Novel Nuclear Receptor Ligand, Digoxigenin, is a Selective Antagonist of Liver-X-receptors, Chem. Lett., 46, 313-314 (2017).


  1. N. Shinohara, N. Sunagawa, S. Tamura, R. Yokoyama, M. Ueda, K. Igarashi, K. Nishitani, The plant cell-wall enzyme AtXTH3 catalyses covalent cross-linking between cellulose and cello- oligosaccharide. Sci. Rep. 7, 46099; doi: 10.1038/srep46099 (2017). Selected as an F1000 article.

 

 

2016


  1. Y. Kanno, T. Oikawa, Y. Chiba, Y. Ishimaru, T. Shimizu, N. Sano, T. Koshiba, Y. Kamiya, M. Ueda, M. Seo, AtSWEET13 and AtSWEET14 regulate gibberellin-mediated physiological processes, Nature Commun. 7:13245 | DOI: 10.1038/ncomms13245 (2016).Selected as an F1000 article.


  1. S. Egoshi, Y. Takaoka, H. Saito, Y. Nukadzuka, K. Hayashi, Y. Ishimaru, H. Yamakoshi, K. Dodo, M. Sodeoka, M. Ueda, Dual function of coronatine as a bacterial virulence factor against plant: possible COI1-JAZ-independent role, RSC Adv., 6, 19404-19412 (2016).


  1. Y. Takaoka, M. Shigenaga, Y. Nukadzuka, M. Imai, Y. Ishimaru, K. Saito, R. Yokoyama, K. Nishitani, M. Ueda, Protein Ligand-tethered Synthetic Calcium Indicator for Localization Control and Spatiotemporal Calcium Imaging in Plant Cells, Bioorg. Med. Chem. Lett., 26, 9-14 (2016).


  1. T. Kobayashi, R. Nakanishi Itai, T. Senoura, T. Oikawa, Y. Ishimaru, M. Ueda, H. Nakanishi, N. K. Nishizawa, Jasmonate signaling is activated in the very early stages of iron deficiency responses in rice roots, Plant Mol. Biol., 91, 533-547 (2016).


  1. 上田 実、「生物の謎に挑む天然物ケミカルバイオロジー」、化学工業(特集 ケミカルバイオロジーの新展開)、67682-686 (2016).


  1. 上田 実、「ディビジョントピックス 天然物の標的選択性を立体異性体で制御する」、化学と工業、69, 236 (2016).



2015


  1. H. Saito, T. Oikawa, S. Hamamoto, Y. Ishimaru, T. Utsumi, J. Chen, M. Kanamori, Y. Sasaki-Sekimoto, M. Shimojima, S. Masuda, Y. Kamiya, M. Seo, N. Uozumi, M. Ueda, H. Ohta, The jasmonate-responsive GTR1 transporter is required for gibberellin-mediated stamen development in Arabidopsis, Nature Commun. 6: 6095 doi: 10.1038/ncomms7095 (2015).


  1. M. Ueda, G. Yang, Y. Nukadzuka, Y. Ishimaru, S. Tamura, Y. Manabe, Functional importance of the sugar moiety of jasmonic acid glucoside for bioactivity and target affinity, Org. Biomol. Chem., 13, 55-58 (2015).


  1. K. Kurotani, K. Hayashi, S. Hatanaka, Y. Toda, D. Ogawa, H. Ichikawa, Y. Ishimaru, R. Tashita, T. Suzuki, M. Ueda, T. Hattori, S. Takeda, Elevated levels of CYP94 family gene expression alleviate the jasmonate response and enhance salt tolerance in rice, Plant Cell Physiol., 56, 779-789 (2015).


  1. K. Bashir, Y. Ishimaru, R. Nakanishi Itai, T. Senoura, M. Takahashi, G. An, T. Oikawa, M. Ueda, A. Sato, N. Uozumi, H. Nakanishi, and N. K Nishizawa, Iron deficiency regulated OsOPT7 is essential for iron homeostasis in rice, Plant Mol. Biol., 88, 165-176 (2015).


  1. 上田 実、「植物の運動を引き起こす化学物質」、現代化学、印刷中 (2015).


  1. 上田 実、「生理活性天然物の作用メカニズム」、生体の科学[特集]使える最新ケミカルバイオロジー、66151-155 (2015).


  1. 上田 実編著、「CSJカレントレビュー19 生物活性分子のケミカルバイオロジー:標的同定と作用機構(書籍)」、化学同人 (2015):上田執筆分「第2章 生物活性リガンド分子標的の基礎」、「第15章 ”Glycosylation Switching”による内因性リガンドの活性制御」


  1. 上田 実、「植物の不思議と化学物質」、河北新報、2015年3月10日から15日(連載).



2014


  1. 上田 実、「植物の就眠ならびに補虫運動の制御機構の化学的解明」、植物の生長調節491-9 (2014).


  1. 上田 実、江越脩祐、植物の生体機能を制御する分子とその作用機構、ファルマシア、50, 1081-1085 (2014).



2013


  1. S. Tamura, S. Inomata, M. Ebine, T. Genji, I. Iwakura, M. Mukai, M. Shoji, T. Sugai, M. Ueda, Triazoyl-Phenyl Linker System Enhancing Aqueous Solubility of Molecular Probe and Efficiency in Affinity Labeling of Target Protein for Jasmonate Glucoside, Bioorg. Med. Chem. Lett. 23, 188-193 (2013).


  1. E. Suzuki, M. Ueda, S. Ohba, T. Sugai, M. Shoji, Stereoselective Construction of cis-Decalin Framework via Radical Domino Cyclization, Tetrahedron Lett., 54, 1589-1592 (2013).


  1. S. Inomata, M. Ueda, T. Sugai, M. Shoji, Synthesis of methyl epi-anhydroquinate utilizing [2,3]-sigmatropic rearrangment of iodosoalkene, Chem. Lett., 42, 1273-1275 (2013).


  1. Y. Ikuta, Y. Koseki, T. Murakami, M. Ueda, H. Oikawa, and H. Kasai, Fabrication of Pure Nanodrugs of Podophyllotoxin Dimer and Their Anticancer Activity, Chem. Lett., 48, 900-901  (2013).


  1. 源治尚久、上田 実、天然物リガンドの標的タンパク質をいかに捕まえるか?、化学と生物、5190-97 (2013).



2012


  1. H. Kasai, T. Murakami, Y. Ikuta, Y. Koseki, K. Baba, H. Oikawa, H. Nakanishi, M. Okada, M. Shoji, M. Ueda, H. Imahori, and M. Hashida, Creation of Pure Nanodrugs and Their Anticancer Properties, Angew. Chem. Int. Ed., 51, 10315-10318 (2012).


  1. M. Ueda, G. Yang, Y. Ishimaru, S. Tamura, T. Itabashi, K. Kiyota, S. Kuwahara, S. Inomata, M. Shoji, T. Sugai, Hybrid Stereoisomers of Compact Molecular Probes Based on Jasmonic Acid Glucoside: Syntheses and Biological Evaluations, Bioorg. Med. Chem., 20, 5832-5843 (2012).


  1. M. Ueda, Chemical Biology of Natural Products on the Basis of Identification of Target Proteins (Highlight Review), Chem. Lett., 41, 658-666 (2012).



2011


  1. M. Ueda, Y. Manabe, Y. Otsuka, N. Kanzawa, Cassia occidentalis MetE as a cytosolic target for potassium isolespedezate, a leaf-opening factor of Cassia plants: target exploration by compact molecular probe (CMP) strategy, Chem. Asian J., 6, 3287-3297 (2011). VIP & Cover picture.


  1. Y. Nakamura, A. Mithöfer, E. Kombrink, W. Boland, S. Hamamoto, N. Uozumi, K. Tohma, M. Ueda, 12-Hydroxyjasmonic Acid Glucoside is a COI1-JAZs Independent Activator of Leaf Closing Movement in Samanea saman, Plant Physiol., 155, 1226-1236 (2011).


  1. Y. Nakamura, S. Inomata, M. Ebine, Y. Manabe, I. Iwakura, M. Ueda, “Click-made” biaryl-linker improving efficiency in protein labelling for the membrane target protein of a bioactive compound, Org. Biomol. Chem., 9, 83-85 (2011).


  1. M. Ueda, Y. Manabe, M. Mukai, The high-performance of 3XFLAG for target purification of bioactive metabolite:  a tag combined with highly effective linker structure, Bioorg. Med. Chem. Lett., 21, 1359-1362 (2011).


  1. 上田 実、生物現象の天然物科学、化学工業(特集 これからの天然物化学)、62597-600 (2011).



2010


  1. M. Ueda, T. Tokunaga, M. Okada, Y. Nakamura, N. Takada, R. Suzuki, K. Kondo, Trap-closing Chemical Factors of Venus’s Flytrap, ChemBioChem, 11, 2378-2383 (2010).


  1. Y. Manabe, M. Mukai, S. Ito, N. Kato, M. Ueda, FLAG Tagging by CuAAC and Nano-gram Scale Purification of the Target Protein for Bioactive Metabolite Concerning Circadian Rhythmic Leaf Movement of Leguminosae, Chem. Commun., 46, 469 – 471 (2010).


  1. M. Okada, Y. Egoshi, M. Ueda, Azido-coronatine: a Useful Platform for “Click Chemistry”-mediated Probe Synthesis for Bioorganic Studies, Biosci. Biotechnol. Biochem., 74, 2092-2095 (2010).


  1. Y. Nakamura, Y. Manabe, S. Inomata, and M. Ueda, Recent Advances on Bioorganic Chemistry of Plant Metabolites Controlling Nyctinasty, The Chemical Record, 10, 70-79 (2010).


  1. 真鍋良幸、猪俣 翔、上田 実、マメ科植物の就眠運動を制御する配糖体型生理活性物質のケミカルバイオロジー、TIGG Review, 22, 31-45 (2010).


  1. 上田 実、中村葉子、ジャスミンの香気成分誘導体と植物の就眠運動、AROMA RESEARCH, 11, 65-69 (2010).



2009


  1. M. Shoji, E. Suzuki, M. Ueda, Total Synthesis of (±)-5-Deoxystrigol via Reductive Carbon-Carbon Bond Formation, J. Org. Chem., 74, 3966-3969 (2009).


  1. M. Okada, S. Ito, A. Matsubara, I. Iwakura, S. Egoshi, M. Ueda, Total Syntheses of Coronatines by exo-Selective Diels-Alder Reaction and Their Biological Activities on Stomatal Opening, Org. Biomol. Chem., 7, 3065–3073 (2009). Selected as an inside front cover.


  1. M. Okada, S. Park, T. Koshizawa, M. Ueda, (R)-Eucomic Acid, a Leaf-opening Factor of the Model Organism, Lotus japonicus, Tetrahedron, 65, 2136-2141 (2009).


  1. 上田 実、中村葉子、真鍋良幸、植物生理活性物質のケミカルジェネティックス、細胞工学、28(4月号)、354-359 (2009).


  1. 上田 実、中村葉子、植物就眠運動のケミカルバイオロジー、化学と生物、47、121-127 (2009).


  1. 中村葉子、上田 実、不思議な生物現象の有機化学–植物の就眠運動を化学する、化学と教育、57No.3)、134-135 (2009).



2008


  1. Y. Nakamura, R. Miyatake, M. Ueda, Enantiodifferential Approach for the Detection of the Target Membrane Protein of the Jasmonate Glycoside That Controls the Leaf Movement of Albizzia saman, Angew. Chem. Int. Ed., 47, 7289-7292 (2008).


  1. E. Kato, T. Sasaki, M. Ueda, Affinity Purification and Characterization of a Key Enzyme Concerning Circadian Rhythmic Control of Nyctinasty in Lespedeza cuneata L. Bioorg. Med. Chem., 16, 4600-4616 (2008).


  1. Y. Nakamura, R. Miyatake, S. Inomata, M. Ueda, Synthesis of Potassium -D-Glucopyranosyl 12-Hydroxy Jasmonate and Related Compounds. Biosci. Biotechnol. Biochem., 72, 2867-2876 (2008).


  1. M. Okada, A. Matsubara, M. Ueda, Synthesis of Photoaffinity Probe Based on the Leaf-opening Factor from Genus Albizzia, Tetrahedron Lett., 49, 3794-3796 (2008).


  1. T. Fujii, N. Kato, I. Iwakura, Y. Manabe, M. Ueda, Synthesis of Staudinger-type Molecular probe for Catch-and–release Purification of the Binding Protein for Potassium Isolespedezate, a leaf-closing Substance of Leguminous Plant, Chem. Lett., 37, 52-53 (2008).


  1. 上田 実、中村葉子、岡田正弘、植物の就眠運動と食虫植物の”記憶”現象の生物有機化学、植物の生長調節、4261-71 (2008).


  1. 中村葉子、真鍋良幸、上田 実、ここまでわかった「動く植物」の謎、化学(5月号)、6326-31(2008).

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